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Titlebook: Cytotoxic, Mutagenic and Carcinogenic Potential of Heavy Metals Related to Human Environment; Nick D. Hadjiliadis Book 1997 Springer Scien

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Pathways in the Chromium(VI)-Mediated Formation of DNA Lesions: A Reviewn cells with chromium(VI). The finding that chromium(VI) itself is unreactive towards DNA [13, 14] has prompted research into the reductive conversion of chromium(VI), ultimately to chromium(III), as a crucial step in the formation of DNA lesions.
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Perinatal Effects of Metals and Cancer in Offspringto lead [5] and methylmercury [6]. In addition, over the last several years, evidence has been accumulating from both epidemiological and experimental investigations that perinatal exposure to metals may result in a later increase in risk for cancer. This evidence is reviewed here.
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Gary Phillips,Donald J. Scellator of metal-induced promutagenic DNA damage are particularly strong for two most powerful human metal carcinogens, nickel and chromium. However, without excluding various pathogenic effects caused by non-redox interactions, oxidative damage tends to take the leading role in explaining the mechanisms
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Gary Phillips,Donald J. Scellatowhile others are more general. In certain cases, the direct recognition signals, conferred by specific metal-binding sites on cell membranes, can result in signal transduction reactions in specific organs. A number of metals, particularly from industrial sources, are non-essential and are toxic to c
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https://doi.org/10.1007/978-1-4613-2535-2roid hormone increases gastrointestinal aluminum absorption on rats and changes its tissue distribution: increases aluminum levels in bones, kidney, muscle and the gray matter of brain. (d) Toxid effects of aluminum have been observed in a variety of organisms i.e. bacteria, a number of protozoa, in
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Zinc Finger-DNA Interaction: Effect of Metal Replacement, Free Radical Generation and DNA Damage andthe regions and encodes the DNA binding domain. This region is connected to the region of next highest conservation, the E region, by the hinge or D region. The E region constitutes the hormone binding domain. It also contains transactivating and dimerization functions. The DNA binding domain C of t
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