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Titlebook: Cytoskeleton of the Nervous System; Ralph A. Nixon,Aidong Yuan Book 2011 Springer Science+Business Media, LLC 2011

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发表于 2025-3-21 18:58:22 | 显示全部楼层 |阅读模式
书目名称Cytoskeleton of the Nervous System
编辑Ralph A. Nixon,Aidong Yuan
视频video
概述Describes cytoskeleton in axonal development and pathology, microtubules and associated proteins, neurofilaments and interacting proteins, actin and its binding proteins, and glial fibrillary acidic p
丛书名称Advances in Neurobiology
图书封面Titlebook: Cytoskeleton of the Nervous System;  Ralph A. Nixon,Aidong Yuan Book 2011 Springer Science+Business Media, LLC 2011
描述This monograph begins with a general description of the cytoskeleton in axonal development and pathology and then moves to more detailed descriptions of particular components, including microtubules and associated proteins, neurofilaments and interacting proteins, actin and its binding proteins, and glial fibrillary acidic protein. The later chapters focus on the functional significance of the neuronal cytoskeleton in axonal transport and its regulation in health and disease states. The Cytoskeleton of the Nervous System will encourage further development of unifying principles and stimulate new conceptual and technical approaches toward a better understanding of cytoskeleton functions in health and disease.
出版日期Book 2011
版次1
doihttps://doi.org/10.1007/978-1-4419-6787-9
isbn_softcover978-1-4939-5142-0
isbn_ebook978-1-4419-6787-9Series ISSN 2190-5215 Series E-ISSN 2190-5223
issn_series 2190-5215
copyrightSpringer Science+Business Media, LLC 2011
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Tauopathy and Brain Aging,ion, and NFTs can be thought of as a tombstone of neuronal dysfunction. Changes in tau may be involved in brain aging and may consequently lead to the formation of NFTs in the entorhinal cortex. This chapter introduces the mechanisms underlying neurodegeneration and brain aging that occur through ta
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Structure of Neural Intermediate Filaments,ural IF can also be deduced, primarily from the pattern of cross-links induced between molecules. Using scanning transmission electron microscopy (STEM) and cryo-tomographic data, the neural IF are likely to have a four-protofibril structure containing 32 chains in section. Assembly occurs through a
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Neurofilament Changes in Multiple Sclerosis,or protein within the axon. Mechanisms of axonal pathology in multiple sclerosis remain unknown, but inflammation in the acute disease phases is likely to cause significant damage. There is also evidence that axonal loss may continue even in the absence of inflammation. It has been postulated that a
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