Titlebook: Cytokines and Growth Factors in Blood Transfusion; Proceedings of the T Cees Th. Smit Sibinga (Initiator and Organiser),P. Conference proce

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Naoto Nemoto,Shigefumi Kumachi,Hidenao Arai cell and platelet transfusion respectively [1]. Whereas the role of leukocyte antibodies, and especially of HLA-antibodies, in causing transfusion reactions was shown in the late 1950’s, it was only recently that it became clear that presensitization might not explain the high reaction rate to plat

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Naoto Nemoto,Shigefumi Kumachi,Hidenao Arai transfer into haematopoietic cells. Gene therapy, however, has potential for the modulation of tumour cell growth, drug sensitivity, and antitumour immune responses. In addition, gene marking can be used, in spite of this limited transfer efficiency, to provide information on haematopoiesis, source

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Mahdi Zeraati,Marcel E. Dinger,Daniel Christnant clone, but also in a number of solid tumours in an effort to increase chemotherapy dose intensity beyond levels of tolerable bone marrow toxicity. Haematopoietic growth factors have been of substantial benefit in improving engraftment kinetics [1]. In recent years, an additional advance has bee

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https://doi.org/10.1007/978-3-642-01147-4e use of mobilized PBPC instead of BM as source of allogeneic stem cells has rapidly expanded [3]. The present article will elucidate the potential benefits and limitations of allogeneic PBPC with particular focus on collection and cellular composition of PBPC grafts obtained from healthy donors.

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Evaluation of Antibody Clonality,in a few hours of the transfusion, or as delayed events, presenting days or possibly years later (Table 1). Patient morbidity is variable depending on the type of reaction and with some reactions mortality can occur [1,2].

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