| 书目名称 | Cytokine Storm Syndrome | | 编辑 | Randy Q. Cron,Edward M. Behrens | | 视频video | | | 概述 | Provides the fundamental basic and applied clinical science at the cutting edge of CSS treatment.Covers all aspects (clinical, genetics, pathophysiology, associations, therapy) as well as new research | | 丛书名称 | Advances in Experimental Medicine and Biology | | 图书封面 |  | | 描述 | .Cytokine Storm Syndromes, including HLH and MAS, are frequently fatal disorders, particularly if not recognized early and treated during presentation. The genetics of Cytokine Storm Syndromes are being defined with many of the risk alleles giving rise to mutations in the perforin-mediated cytolytic pathway used by CD8 cytotoxic T cells and natural killer cells. These are being studied using murine models. Up to 10% of the general population may carry risk alleles for developing Cytokine Storm Syndromes, and Cytokine Storm Syndromes are being increasingly recognized around the world in pediatric and adult hospitals...A variety of infectious, rheumatic, and oncologic triggers are commonly associated with Cytokine Storm Syndromes, but understanding this disorder is critical for all researchers and physicians to ensure timely and appropriate therapy. This second edition addresses all aspects of the disorder, from genetics, pathophysiology, and ongoing research, to clinical presentations, risk factors and treatment. New-to-this-edition features include dedicated chapters on severe COVID-19 CSS, and post-COVID CSS of multi-system inflammatory syndrome in children (MIS-C). In addition, n | | 出版日期 | Book 2024Latest edition | | 关键词 | Hemophagocytic lymphohistiocytosis; Macrophage activation syndrome; Perforin; Cytolysis; Genetics; Cytoki | | 版次 | 2 | | doi | https://doi.org/10.1007/978-3-031-59815-9 | | isbn_softcover | 978-3-031-59817-3 | | isbn_ebook | 978-3-031-59815-9Series ISSN 0065-2598 Series E-ISSN 2214-8019 | | issn_series | 0065-2598 | | copyright | The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Nature Switzerl |
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发表于 2025-3-21 16:53:04
