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Titlebook: Cytokine Frontiers; Regulation of Immune Takayuki Yoshimoto,Tomohiro Yoshimoto Book 2014 Springer Japan 2014 Anti-inflammatory cytokines.Pr

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书目名称Cytokine Frontiers
副标题Regulation of Immune
编辑Takayuki Yoshimoto,Tomohiro Yoshimoto
视频video
概述Includes supplementary material:
图书封面Titlebook: Cytokine Frontiers; Regulation of Immune Takayuki Yoshimoto,Tomohiro Yoshimoto Book 2014 Springer Japan 2014 Anti-inflammatory cytokines.Pr
描述.This book guides the reader through the latest research on the cytokine network, covering signaling pathways, control of the immune response, and potential therapeutics. Different cytokines stimulate diverse responses in various phases of inflammation and immunity, including the innate immune response, the generation of effector T cells, and the development of antibodies by the humoral immune system. It is now clear that the pathophysiology of many infectious, autoimmune, allergic, and malignant diseases can be largely explained by which cytokines are induced and subsequently regulate the cellular responses. In clinical medicine, cytokines are involved in a wide spectrum of diseases. This book describes in three parts the properties and roles of 15 key cytokines under physiological and pathological conditions. Part I presents nine cytokines associated with inflammatory disorders, pro-inflammatory cytokines, and the recently identified new helper T (Th) subset: Th17 cells. Part II gives details of three cytokines associated with allergic disorders, including Th2 responses and recently identified types of innate cells. Part III describes three cytokines that are associated with immu
出版日期Book 2014
关键词Anti-inflammatory cytokines; Pro-inflammatory cytokines; Th2-type cytokines
版次1
doihttps://doi.org/10.1007/978-4-431-54442-5
isbn_softcover978-4-431-56124-8
isbn_ebook978-4-431-54442-5
copyrightSpringer Japan 2014
The information of publication is updating

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The Roles of IL-17A and IL-17F in Infection and Inflammatory Disorders17A among the IL-17 family and binds to the same IL-17 receptor A (IL-17RA) and IL-17RC receptor complex as IL-17A. Recent studies have demonstrated that IL-17A and IL-17F are also produced by multiple lineages of immune cells, including γδ T cells, NKT cells, and innate lymphoid cells. These cytoki
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Interleukin-22: A Bridge Between Epithelial Innate Host Defense and Immune Cellsipheral tissue epithelial cells. IL-22 functions as a unique messenger from immune system to tissue epithelial cells and to regulate homeostasis of epithelia. IL-22 is able to directly enhance antimicrobial defense mechanisms in epithelial cells and to facilitate epithelial barrier repair and wound
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IL-36: An Epithelial Cytokine Important in Psoriasisby epithelial tissues. Similar to other IL-1 family cytokines, they promote inflammatory responses by activating kinases such as JNK, p38, and the IKKs, and activating transcription factors such as NFκB. They only do this, however, after N-terminal processing, which increases their specific activity
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Anti-TNF Therapy: 20 Years from Our First Therapeutic Adventuredisease tissue in rheumatoid arthritis and on exploring the dysregulation of cytokine expression within that tissue..From those first successful clinical trials we conducted in 1992 with infliximab, which were widely publicized more than a year before publication, a competition emerged between a set
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