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Titlebook: Current and Future Immunosuppressive Therapies Following Transplantation; Mohamed H. Sayegh,Giuseppe Remuzzi Book 2001 Springer Science+Bu

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书目名称Current and Future Immunosuppressive Therapies Following Transplantation
编辑Mohamed H. Sayegh,Giuseppe Remuzzi
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图书封面Titlebook: Current and Future Immunosuppressive Therapies Following Transplantation;  Mohamed H. Sayegh,Giuseppe Remuzzi Book 2001 Springer Science+Bu
描述This title provides a comprehensive and state-of-the-artsummary of current and future immunosuppressive strategies intransplantation, with emphasis on the basic science mechanisms andclinical applicability of these strategies. The uniqueness of thisbook is the inclusion of up-to-date information on the basicmechanisms of actions of the immunosuppressive drugs as well as asummary of the clinical trials data and the potential use of thesedrugs in clinical organ transplantation. In addition to describing thevarious immunosuppressive strategies, the book has three specialfeatures, including immunosuppression in xenotransplantation, genetherapy approaches, and transplantation tolerance. A group ofoutstanding investigators have been assembled to write the chapters.The book is intended for the transplant professional and thespecialist who wants to stay abreast of the current status ofimmunosuppression in organ transplantation. The book is also usefulfor basic scientists who work in the field of transplantationimmunology.
出版日期Book 2001
关键词T cell; clinical trial; gene therapy; immunology; immunosuppression; kidney; organ; organ transplantation; t
版次1
doihttps://doi.org/10.1007/978-94-010-1005-4
isbn_softcover978-94-010-3876-8
isbn_ebook978-94-010-1005-4
copyrightSpringer Science+Business Media New York 2001
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12 x 12 Schlüsselkonzepte zur Mathematikore selective and specific agents has become, in the past decade, one of the priorities for transplant medicine. Some of these compounds are now entering routine clinical practice: among them are tacrolimus, mycophenolate mofetil (MMF) and sirolimus.
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50 Schlüsselideen Wirtschaftswissenschaftsm of action of tacrolimus, and then go on to summarize its use as both primary immunosuppressive agent and as rescue agent in adult and pediatric sold organ transplantation (emphasizing the most recent multi-center and selected single center trial data), its dosage, its use in combination with othe
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https://doi.org/10.1007/978-3-8274-2900-1he requirements for immunotherapy. For example, the risk of acute rejection is greater in children, African-Americans and in recipients who are sensitized to HLA [3]. Taken together, these observations have provided the rationale for the development of induction immunosuppressive strategies that min
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https://doi.org/10.1007/978-3-8274-2900-1T3, a murine anti-CD. monoclonal antibody, was introduced in 1986. The mechanism of action of OKT3 consists of T cell depletion and CD. modulation. While the polyclonal agents and OKT3 induce effective immunosuppression, they are also associated with opportunistic infections and post transplant lymp
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https://doi.org/10.1007/978-3-8274-2900-1ation of these molecules and activation events. Furthermore, biological processes have evolved to facilitate these processes in as much as the interaction between cognate antigen and the T cell receptor is a process that facilitates the expression of high affinity adhesion molecules; and disruption
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Pharmacologic Monitoring of Immunosuppressive Drugsore selective and specific agents has become, in the past decade, one of the priorities for transplant medicine. Some of these compounds are now entering routine clinical practice: among them are tacrolimus, mycophenolate mofetil (MMF) and sirolimus.
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