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Titlebook: Current Topics in Clinical Radiobiology of Tumors; Hans-Peter Beck-Bornholdt Book 1993 Springer-Verlag Berlin Heidelberg 1993 DNA.Onkologi

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https://doi.org/10.1007/978-3-319-47886-9ect this fact to result in a reduced probability of local tumor control if the same dose-fractionation schedule were to be applied in a longer overall time. However, independent of any mechanistic considerations at the cellular level, it is a problem for clinical science to decide to what extent an
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Jacob Wood,Stefanie Creedy,Peter Duncansonly the same overall time as in conventional therapy. Its purpose is to increase the biological dose to the tumor without an increase in the biological dose to late-responding normal tissues. Although there are variations among centers in what is “conventional,” for present purposes it is assumed to
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https://doi.org/10.1007/978-3-319-48217-0us tumours, melanomas did not respond well to radiotherapy and did not regress even if doses were escalated to levels which produced very severe skin reactions. Yet tumour regression rate is an inadequate criterion of tumour radiosensitivity, which rather should be based on local tumour control. Aft
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Learning Grasps in a Synergy-based Frameworkmarily relevant in patients receiving treatment for tumors still confined to their original local or local-regional sites. While it is obvious that eradication of the primary tumor is essential for the achievement of cure, several investigators have argued that the presence of incurable micrometasta
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