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Titlebook: Crystallographic and Modeling Methods in Molecular Design; Charles E. Bugg,Steven E. Ealick Book 1990 Springer-Verlag New York, Inc. 1990

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Inhibitor Design from Known Structures, cell membrane. As knowledge of both drugs and disease states has grown, specific receptors have been identified for certain drugs, and target receptors have been identified for some disease states. Any effort to design drugs rationally depends on understanding the intermolecular interactions involv
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Woman-as-Spectacle in Love-Story Films,still susceptible to infection by another. For this reason, vaccines have been developed to prevent poliovirus infection, but the great number of rhinovirus serotypes has thwarted the development of a rhinovirus vaccine. Therefore, in the case of rhinovirus, the only hope for a “cure” seems to lie in a pharmaceutical approach.
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Take All My Wealth and Let My Body Go,es, . and avian malarial parasite (5–15). In general, it appears that the mammalian enzyme is a trimer of identical subunits (16–20) while the bacterial enzyme is a hexamer of identical subunits (21). Both the human erythrocytic PNP and the . PNP have been crystallized (22, 23).
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