Titlebook: Critical Issues in Head and Neck Oncology; Key Concepts from th Jan B. Vermorken,Volker Budach,Brian O‘Sullivan Conference proceedings‘‘‘‘‘

ABASH

Patterns of Response to Immune Oncology Drugs: How Relevant Are They in SCCHN?,nitially in melanoma trials and has been gradually incorporated in the treatment algorithm of a variety of malignancies in multiple settings. Immune checkpoint inhibitors (ICIs), the most widely used immunotherapy drugs, are monoclonal antibodies that target specific immune checkpoints such as Progr

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Precision Medicine in the Treatment of Malignancies Involving the Ventral Skull Base: Present and Fasal sinuses, nasopharynx, and adjacent mesenchymal tissues translates into a proportionally vast spectrum of prognoses, with some histologies such as olfactory neuroblastoma being associated with rare disease-specific death to other histologies such as mucosal melanoma for which survival beyond 5 y

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Targeting Molecular Residual Disease Using Novel Technologies and Clinical Trials Design in Head anave substantial risks of relapse despite definitive therapy, and thus represent conditions of unmet clinical need. The ability now exists to detect molecular residual disease (MRD) in these patients post-definitive treatment such as surgery or (chemo)radiotherapy using novel and highly sensitive and

TERRA

New Developments in Surgery for Malignant Salivary Gland Tumors,tment of choice in most patients. In this respect, recently, interesting developments in ablative and reconstructive procedures have been proposed. Regarding the ablative part, transoral surgery, both with laser (transoral laser microsurgery or TLM) and robot (transoral robotic surgery or TORS) is i

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Eulogy

Administration und Gremienarbeit,al characteristics of the delivered radiation, can all influence the immunogenicity of radiotherapy. By understanding and modulating cross-talk between molecular responses to radiation-induced DNA damage, associated mechanisms of cell death and subsequent innate and adaptive immune responses, we may

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https://doi.org/10.1007/978-3-662-56638-1ENE carries prognostic significance beyond traditional cN classification for both viral-related and unrelated head and neck cancer, and can serve an important role for clinical care and risk stratification. For clinical care, such as triaging HPV-positive oropharyngeal cancer to surgery vs radiother