书目名称 | Contraceptive Steroids | 副标题 | Pharmacology and Saf | 编辑 | A. T. Gregoire,Richard P. Blye | 视频video | | 丛书名称 | The Plenum Behavior Therapy Series | 图书封面 |  | 描述 | One of the United States Food and Drug Administration‘s most difficult tasks is the assessment of risk-benefit ratios for a broad spectrum of therapeutic and prophylactic drugs. Furthermore, it is now widely recog nized that no drug, chemical or even natural substance is completely devoid of risk. Nowhere has this issue been the subject of more controversy than with steroidal contraceptive drugs. Regulated as a special class of products because of their prophylactic use in healthy individuals for prevention of pregnancy rather than for treatment of disease, steroid contraceptives drugs undergo more extensive animal safety tests than any other pharmaceutical agent. This view also contemplates the availability of alternative contraceptive measures posing fewer risks, but the use of less effective methods must take into consideration the hazards associated with pregnancy itself. In April 1983, the Food and Drug Administration and the National Insti tutes of Health in cooperation with the World Health Organization, the Population Council, and the Agency for International Development sponsored a three-day workshop to evaluate current guidelines for preclinical safety studies of contra | 出版日期 | Book 1986 | 关键词 | Lipoprotein; World Health Organization; assessment; drug; kinetics; lipide; metabolism; pharmacokinetics; ph | 版次 | 1 | doi | https://doi.org/10.1007/978-1-4613-2241-2 | isbn_softcover | 978-1-4612-9313-2 | isbn_ebook | 978-1-4613-2241-2 | copyright | Springer Science+Business Media New York 1986 |
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