Titlebook: Computational Systems Toxicology; Julia Hoeng,Manuel C. Peitsch Book 2015 Springer Science+Business Media New York 2015 Biological network

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Methods in Pharmacology and Toxicologyhttp://image.papertrans.cn/c/image/233169.jpg

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Nantgarw Porcelain: Named Services,lationships that focus on smoking-relevant cytochrome P450 (CYP) enzymes. Subsequently, we describe several network-based approaches for toxicity assessment and relevant use cases leveraging a xenobiotic metabolism network model for a quantitative assessment of CS impact.

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Analysis of Proteomic Data for Toxicological Applications,pectrometry data and the identification of affected proteins, functional modules, and protein subnetworks. We illustrate these approaches using results from a 90-day rat inhalation toxicology study. Overall, we provide the foundation to employ quantitative proteomics within systems toxicology assessment strategies.

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https://doi.org/10.1007/978-3-031-43841-7s, Payao as the curation platform, iPathways+ as the publishing platform, and Garuda to integrate curated pathways while adopting model-descriptive standards such as Systems Biology Markup Language as a file format and Systems Biology Graphical Notation as the graphical representation.

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Felix Burgold,Stephan Sonnenburg,Markus Voßfter exposure of cells to chemicals in vitro. The case studies cover various areas of systems toxicology and pharmacogenomics and illustrate the rapid evolution of toxicogenomics, including computational methods for the analysis, integration, and interpretation of omics data.

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OPINE

Weaving Knowledge into Biological Pathways in a Collaborative Manner,s, Payao as the curation platform, iPathways+ as the publishing platform, and Garuda to integrate curated pathways while adopting model-descriptive standards such as Systems Biology Markup Language as a file format and Systems Biology Graphical Notation as the graphical representation.