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Titlebook: Computational Systems Toxicology; Julia Hoeng,Manuel C. Peitsch Book 2015 Springer Science+Business Media New York 2015 Biological network

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Palgrave Studies in Languages at Warhat can cause adverse health effects in humans. This chapter describes analysis methods that can use (1) human transcriptomics data to identify perturbed signaling pathways and (2) animal model data to infer the pathway activity in human for the same stimuli. For the former goal, we describe Pathway
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Medical Management of Swallowing Disorders,proaches measure changes in the levels of proteins and their posttranslational modifications, which can closely reflect the biological effects of a toxicant. With a focus on mass spectrometry-based proteomics, we describe the isobaric tag-based approach for quantitative proteomics (iTRAQ. and TMT.)
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Felix Burgold,Stephan Sonnenburg,Markus Voßrating and analyzing multi-omics data have facilitated the development of toxicogenomics to provide novel answers to many toxicology-related questions. In this chapter, we discuss five recent toxicogenomics studies presenting complementary strategies for mining genome-wide molecular profiling data a
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