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Titlebook: Computational Neuroscience of Drug Addiction; Boris Gutkin,Serge H. Ahmed Book 2012 Springer Science+Business Media, LLC 2012

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发表于 2025-3-21 16:20:09 | 显示全部楼层 |阅读模式
书目名称Computational Neuroscience of Drug Addiction
编辑Boris Gutkin,Serge H. Ahmed
视频video
概述Intrigued by the apparent irrational behavior of drug addicts, researchers from a wide range of scientific disciplines have formulated a plethora of theoretical schemes over the years to understand ad
丛书名称Springer Series in Computational Neuroscience
图书封面Titlebook: Computational Neuroscience of Drug Addiction;  Boris Gutkin,Serge H. Ahmed Book 2012 Springer Science+Business Media, LLC 2012
描述Drug addiction remains one of the most important public health problems in western societiesand is a rising concern for developing nations. Over the past 3 decades, experimental research on theneurobiology and psychology of drug addiction has generated a torrent of exciting data, from the molecular up to the behavioral levels. As a result, a new and pressing challenge for addiction research is to formulate a synthetic theoretical framework that goes well beyond mere scientific eclectism to deepen our understanding of drug addiction and to foster our capacity to prevent and to cure drug addiction.Intrigued by the apparent irrational behavior of drug addicts, researchers from a wide range of scientificdisciplines have formulated a plethora of theoretical schemes over the years to understand addiction.However, most of these theories and models are qualitative in nature and are formulated using terms that are often ill-defined. As a result, the empirical validity of these models has been difficult to test rigorously, which has served to generate more controversy than clarity. In this context, as in other scientific fields, mathematical and computational modeling should contribute to th
出版日期Book 2012
版次1
doihttps://doi.org/10.1007/978-1-4614-0751-5
isbn_softcover978-1-4614-2940-1
isbn_ebook978-1-4614-0751-5Series ISSN 2197-1900 Series E-ISSN 2197-1919
issn_series 2197-1900
copyrightSpringer Science+Business Media, LLC 2012
The information of publication is updating

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Book 2012ing terms that are often ill-defined. As a result, the empirical validity of these models has been difficult to test rigorously, which has served to generate more controversy than clarity. In this context, as in other scientific fields, mathematical and computational modeling should contribute to th
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Intermittent Adaptation: A Mathematical Model of Drug Tolerance, Dependence and Addictionusly functioning adaptation processes. Simulations with the mathematical model demonstrate the model’s behaviour to be consistent with important characteristics of the development of tolerance to repeatedly administered drugs: the gradual decrease in drug effect when tolerance develops, the high sen
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Dual-System Learning Models and Drugs of Abusewell as on other processes..Here, we seek a more parsimonious account of these phenomena by asking whether the apparent profligacy of drugs’ effects might be explained by a single mechanism of action. In particular, we propose that the pattern of effects observed under drug abuse may reveal interact
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Computational Models of Incentive-Sensitization in Addiction: Dynamic Limbic Transformation of Learn-based models of reinforcement and reward learning. Our motivation-based model incorporates dynamically modulated physiological brain states that change the ability of cues to elicit ‘wanting’ on the fly. These brain states include the presence of a drug of abuse and longer-term mesolimbic sensitiza
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Toward a Computationally Unified Behavioral-Economic Model of Addictionng the scope of an explanatory concept is introduced via consideration of the concept of unit price. This concept integrates numerous variables traditionally studied in isolation in addiction research, and provides the basis of more general and parsimonious explanations of addiction phenomena. The s
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