Titlebook: Computational Intelligence Methods for Bioinformatics and Biostatistics; 6th International Me Francesco Masulli,Leif E. Peterson,Roberto Ta

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,Kurzlösungen zu den Übungsaufgaben,xpression variation across groups of treatment..Because of the non-normal distribution of data, non-parametric methods based on the MANOVA approach and the use of permutations to obtain global F-ratio tests have been proposed to deal with this problem. The issue of analyzing univariate contrasts is

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,Kurzlösungen zu den Übungsaufgaben, the validity of the analytical results. Hence attention has to be given to some form of dimension reduction to represent the data in terms of a smaller number of variables. The latter are often chosen to be a linear combinations of the original variables (genes) called metagenes. One commonly used

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