Titlebook: Cognitive Enhancing Drugs; Jerry J. Buccafusco Book 2004 Birkhäuser Verlag 2004 Alzheimer.attention.cholinesterase.cns.cognitive disorders

半球

Peptide and steroid hormone receptors as drug targets for enhancement of learning and memory perfor“Then Dr Strauss said Charlie even if this fales your making a grate contribyushun to sience. This experimint has been successful on lots of animals but its never bin tried on a humen being. You will be the first. After the operashun Im gonna try to be smart. Im gonna try awful hard.” (sic) p. 8, Flowers For Angernon [1]

SLUMP

Reverie

https://doi.org/10.1007/978-0-387-33244-4 a first generation of drugs such as physostigmine and tacrine, a second generation of more suitable compounds was developed in the 1990s. These drugs are clinically more efficacious and produce less severe side-effects at effective doses. Contrary to the discovery of other neurotransmitter-based CN

Agnosia

https://doi.org/10.1007/978-0-387-33244-4nd cerebral cortex arise from basal forebrain nuclei, including the medial septum (MS, Ch1 group), the vertical and horizontal limbs of the diagonal band (Ch2 and Ch3) and the nucleus basalis of Meynert (NBM, Ch4) [2]. Cholinergic neurons arising from the MS project mainly to the hippocampus, a brai

啜泣

https://doi.org/10.1007/978-0-387-33244-4e, Alzheimer’s disease, anxiety, autism, depression, epilepsy, Parkinson’s disease, schizophrenia, and Tourette’s syndrome [1,2]. Mechanisms of nAChR impairment in this disparate group of syndromes are poorly understood. Additionally, in healthy organisms nAChRs play a significant role in a number o

他日关税重重

https://doi.org/10.1007/978-0-387-33244-4s using the neurotransmitters, dopamine (DA) and norepinepherine (NE) play important roles in a wide variety of neurobehavioral functions including cognition. DA neurons from the substantia nigra (SN) prject primarily to the striatum, while DA neurons from the nearby ventral tegmental area (VTA) pro

Talkative

https://doi.org/10.1007/978-0-387-33244-4 reports of its actions on smooth muscle appeared more than 50 years ago and it is now known to have widespread peripheral and central physiologic actions. In the periphery, the amine is released from platelets to activate clotting cascades and blood vessel constriction; in the gastrointestinal trac

挑剔小责

https://doi.org/10.1007/978-0-387-33244-4t became evident that multiple receptor subtypes were responsible for the physiological properties of glutamatergic neurotransmission [4]. Thanks to the combined efforts of physiology, molecular biology and pharmacology we gained a complex picture of the various types and flavours of ionotropic and

expound