Titlebook: Cognitive Enhancing Drugs; Jerry J. Buccafusco Book 2004 Birkhäuser Verlag 2004 Alzheimer.attention.cholinesterase.cns.cognitive disorders

出处

https://doi.org/10.1007/978-0-387-33244-4tential for drugs that interdict the histaminergic pathways in various neurological diseases, particularly those having a cognitive deficit that these drugs may be anticipated to ameliorate (see Fig. 1 for chemical structures of key compounds discussed).

极深

感染

Drugs that target catecholaminergic receptors,of the cortex, limbic system and thalamus. These projections serve as the basis of CA involvement in cognitive function particularly in aspects of the relationship of arousal and attention to salient sensory cues [1]. CA neurons and their post-synaptic receptors are targets for therapeutic treatments for a variety of cognitive disorders [2].

积云

Cognitive enhancing effects of drugs that target histamine receptors,tential for drugs that interdict the histaminergic pathways in various neurological diseases, particularly those having a cognitive deficit that these drugs may be anticipated to ameliorate (see Fig. 1 for chemical structures of key compounds discussed).

Femish

pacific

Drugs that target serotonergic receptors,t it inhibits gastric acid production and stimulates the contractions of smooth muscle [1]. In the central nervous system, 5HT is known to regulate or influence such diverse processes as activity patterns and circadian rhythm, food intake, sleep-wake cycles, aggressive behaviors, locomotion, thermoregulation, nociception, and sexual activity [2].

CESS

梯田

,The cholinergic hypothesis — past and present,lcholinesterase (AChE), the enzyme that degrades synaptically-released acetylcholine. Despite this important application of the hypothesis, the origin of the cholinergic theory likely derives mainly from the effects produced by anticholinergic drugs, chiefly natural products like atropine and scopol

易发怒

ordain