Titlebook: Clostridium difficile; Methods and Protocol Adam P. Roberts,Peter Mullany Book 2016Latest edition Springer Science+Business Media New York

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书目名称Clostridium difficile影响因子(影响力)




书目名称Clostridium difficile影响因子(影响力)学科排名




书目名称Clostridium difficile网络公开度




书目名称Clostridium difficile网络公开度学科排名




书目名称Clostridium difficile被引频次




书目名称Clostridium difficile被引频次学科排名




书目名称Clostridium difficile年度引用




书目名称Clostridium difficile年度引用学科排名




书目名称Clostridium difficile读者反馈




书目名称Clostridium difficile读者反馈学科排名

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, Genome Editing Using , Alleles,d subsequent isolation of double-crossover excision events using replication-defective plasmids that carry a counterselection marker. Use of a . (cytosine deaminase) or . (orotate phosphoribosyltransferase) as counter selection markers appears equally effective, but there is considerable merit in us

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, Adhesins,ence and on the other on the host. The pathogenesis of . infection could be seen as a three-step process that takes place after disruption of the digestive microbiota by antibiotics: (1) contamination by and germination of spores; (2) multiplication of vegetative cells in the colonic niche using col

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Intestinal Epithelial Cell Response to , Flagella,and animals, produces toxins that are known to contribute directly to damage of the gut. It is known that bacterial flagella are involved in intestinal lesions through the inflammatory host response. The . flagellin recognizes TLR5 and consequently activates the NF-κB and the MAPK signaling pathways

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Inducing and Quantifying , Spore Formation,aerobe to form metabolically dormant spores that can resist antibiotic treatment, survive exit from the mammalian host, and transmit . infections. In this chapter, we describe a method for inducing . sporulation in vitro. This method can be used to study sporulation and maximize spore purification y

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Characterization of Functional Prophages in ,,ated within the chromosome of their host, or as episomal DNAs. Since prophages are ubiquitous throughout the bacterial world, there has been a sustained interest in trying to understand their contribution to the biology of their host. . is no exception to that rule and with the recent release of hun