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Titlebook: Clinical Pharmacology of Learning and Memory; Walter B. Essman Book 1983 Spectrum Publications, Inc. 1983 pharmacology

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发表于 2025-3-21 18:01:05 | 显示全部楼层 |阅读模式
书目名称Clinical Pharmacology of Learning and Memory
编辑Walter B. Essman
视频video
图书封面Titlebook: Clinical Pharmacology of Learning and Memory;  Walter B. Essman Book 1983 Spectrum Publications, Inc. 1983 pharmacology
描述The search for drugs to alter learning and memory processes in animals and man has its roots in mythology as well as the history of medicine. The use of plant alkaloids to improve memory was a recommendation of Benjamin Rush in his "Diseases of the Mind" (1812, P. 284), and the mysterious contents of lethe, a liquid capable of causing the erasure of earthly memories is found in Egyptian and Greek mythology, as well as described by Dante, remains a still-sought amnesic molecule. The facilitation of learning or improvement of memory has been claimed for several plant-derived substances including coca, chat, caffeine, and nicotine. Hypotheses concerning substances found in the brain and their presumed significance for learning or memory led to the development and use of agents that contained such substances. For example, as observed by William James (1892, P. 132), the emphasis, in Germany during the 1860‘s, upon phosphorus in the brain for cognitive functions gave rise to the suggestion that foods vii viii CLINICAL PHARMACOLOGY OF LEARNING AND MEMORY high in phosphorus content, such as fish, were good for brain function. Phosphorus-containing preparations were advocated for use in ca
出版日期Book 1983
关键词pharmacology
版次1
doihttps://doi.org/10.1007/978-94-011-9658-1
isbn_softcover978-94-011-9660-4
isbn_ebook978-94-011-9658-1
copyrightSpectrum Publications, Inc. 1983
The information of publication is updating

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发表于 2025-3-21 21:05:06 | 显示全部楼层
Macromolecules in Learning and Memory,puts to the central nervous system alter the ionic equilibrium of the cell cytoplasm and modify the stability of the nitrogenous bases of the RNA molecule (Hydén, 1959). Altered molecular structure through base modification leads to the synthesis of new RNA-dependent proteins capable of interacting
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Serotonin in Learning and Memory,mine and in amnesic agents or events, but also from pharmacological studies. An early study (Woolley, 1965) found that mice with an elevated brain serotonin level produced with a combination of 5-hydroxytryptophan (60 mg/kg) and benzlmethoxytryptamine (15 mg/kg) had a 13% reduction in the average nu
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Barbiturates and Sedatives,anges in brain biogenic amines to changes in learning and memory. These classes of drug include the barbiturates and the benzodiazepines. The effects of representative agents upon the regional turnover of serotonin have been studied, and a generalized decrease was observed (Lidbrink et al., 1974). S
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Mood Alterants,n may also be given to agents that have been employed clinically as mood stabilizers. Among these are the tricyclic compounds commonly utilized for the treatment of depression. It may be recalled, as mentioned earlier, that at least one biochemical effect of agents in this class is to impair the nor
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Stimulants,le, interruption of the ascending serotonin ergic pathways in the rat with lesions of the medial forebrain bundle, leading to a 60–84% decrease in telencephalic serotonin, produced a threefold enhancement of amphetamine effect (Green and Harvey, 1974). An increased rate of operant conditioning respo
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