书目名称 | Cirrhosis, Hyperammonemia, and Hepatic Encephalopathy | 编辑 | Santiago Grisolía,Vicente Felipo | 视频video | | 丛书名称 | Advances in Experimental Medicine and Biology | 图书封面 |  | 描述 | This volume contains the papers presented in the International Summer Course on "Cirrhosis, Hyperammonemia and Hepatic Encephalopathy," which was one of the prestigious Summer Course, of the Complutense University of Madrid held in EI Escorial, Spain, during August 10-14, 1992. Liver cirrhosis is one of the main causes of death in western countries. In addition there is a series of liver dysfunctions including fulminant hepatic failure, Reye‘s syndrome and congenital defects of urea cycle enzymes that could lead to hepatic encephalopathy, coma and death. As a consequence of impaired liver function, the ability to detoxify ammonia by its incorporation into urea is diminshed, resulting in increased ammonia levels in blood and brain. Hyperammonemia is considered one of the main factors in the mediation of hepatic encephalopathy and the classical clinical treatments are directed towards reducing blood ammonia levels. A part of the book is therefore devoted to the study of certain aspects of ammonia metabolism such as the regulation of the urea cycle, the main mechanism of ammonia detoxification in mammals, which is located mainly in the liver. The metabolism of ammonia in other tissues | 出版日期 | Book 1993 | 关键词 | brain; death; liver; metabolism; nutrition; tissue; hepatology | 版次 | 1 | doi | https://doi.org/10.1007/978-1-4615-2484-7 | isbn_softcover | 978-1-4613-6058-2 | isbn_ebook | 978-1-4615-2484-7Series ISSN 0065-2598 Series E-ISSN 2214-8019 | issn_series | 0065-2598 | copyright | The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Science+Busines |
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