书目名称 | Chronic Myeloid Leukemia | 编辑 | Rüdiger Hehlmann | 视频video | | 概述 | Presents state-of-the-art reviews of key issues relating to chronic myeloid leukemia.Covers a wide range of management topics.Discusses prognostic aspects and early response prediction.Examines the ch | 丛书名称 | Hematologic Malignancies | 图书封面 |  | 描述 | .This book provides state-of-the-art reviews of key issues and recent developments relating to chronic myeloid leukemia (CML), acquainting the reader with advances in research, treatment, and promotion of public health. Among the management topics addressed are the choices, advantages, and pitfalls of first-, second-, and third-line treatments; the European LeukemiaNet recommendations; management of adverse effects of tyrosine kinase inhibitors (TKI); management of CML blast crisis; management of pregnancy in the context of CML; the role of hematopoietic cell transplantation; the current experience with TKI discontinuation; and the value of interferon α in improving the outcome of TKI treatment. Various aspects of relevance to treatment outcome are discussed, including prognostic scores, molecular monitoring (principles and interlaboratory standardization), and response-related predictors of survival. Furthermore, updates are provided on the increasing prevalence of CML and its implications and on the changing cost of care for CML, taking into account the impact of availability of generic imatinib. . | 出版日期 | Book 2021Latest edition | 关键词 | Chronic myeloid leukaemia; BCR-ABL; Tyrosine kinase inhibitors; Philadelphia chromosome; Fertility; Hemat | 版次 | 2 | doi | https://doi.org/10.1007/978-3-030-71913-5 | isbn_softcover | 978-3-030-71915-9 | isbn_ebook | 978-3-030-71913-5Series ISSN 2197-9766 Series E-ISSN 2197-9774 | issn_series | 2197-9766 | copyright | The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Nature Switzerl |
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