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Titlebook: Chronic Myeloid Leukemia; Rüdiger Hehlmann Book 20161st edition Springer International Publishing Switzerland 2016 Chronic myeloid leukaem

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书目名称Chronic Myeloid Leukemia
编辑Rüdiger Hehlmann
视频videohttp://file.papertrans.cn/227/226396/226396.mp4
概述Presents state-of-the-art reviews of key issues relating to chronic myeloid leukemia.Covers a wide range of management topics.Discusses prognostic aspects and early response prediction.Examines the ch
丛书名称Hematologic Malignancies
图书封面Titlebook: Chronic Myeloid Leukemia;  Rüdiger Hehlmann Book 20161st edition Springer International Publishing Switzerland 2016 Chronic myeloid leukaem
描述.This book provides state-of-the-art reviews of key issues and recent developments relating to chronic myeloid leukemia (CML), acquainting the reader with advances in research, treatment, and promotion of public health. Among the management topics addressed are the choices, advantages, and pitfalls of first-, second-, and third-line treatments; the European LeukemiaNet recommendations; management of adverse effects of tyrosine kinase inhibitors (TKI); management of CML blast crisis; management of pregnancy in the context of CML; the role of hematopoietic cell transplantation; the current experience with TKI discontinuation; and the value of interferon α in improving the outcome of TKI treatment. Various aspects of relevance to treatment outcome are discussed, including prognostic scores, molecular monitoring (principles and interlaboratory standardization), and response-related predictors of survival. Furthermore, updates are provided on the increasing prevalence of CML and its implications and on the changing cost of care for CML, taking into account the forthcoming impact of availability of generic imatinib. .
出版日期Book 20161st edition
关键词Chronic myeloid leukaemia; BCR-ABL; Tyrosine kinase inhibitors; Philadelphia chromosome; Fertility; Hemat
版次1
doihttps://doi.org/10.1007/978-3-319-33198-0
isbn_softcover978-3-319-81451-3
isbn_ebook978-3-319-33198-0Series ISSN 2197-9766 Series E-ISSN 2197-9774
issn_series 2197-9766
copyrightSpringer International Publishing Switzerland 2016
The information of publication is updating

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Barbara Friebertshäuser Dr. phil.ility and safety issues have not been fully elucidated at present, especially for new-generation TKIs. Recent evidence has emerged that these new agents may sometimes impinge on vital organs such as the heart and lung in an irreversible fashion especially when comorbidities are present; thus, decisi
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Reflexive Ethnographic Practice survival of these patients. In recent population-based studies, CML patients have an overall survival that is comparable to that shown in large clinical trials, though relative survival in patients >70 years is still decreased. The importance of socioeconomic factors and health-care setting for out
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Anwendungen des RGTM-Forschungsstils,es with imatinib therapy. However, the undesirable side effects of IFNα can make this therapy difficult to deliver, and the optimal therapeutic window for using IFNα in combination therapy is unknown. Further studies are needed to clarify the best niche for IFNα use in CML.
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Book 20161st editions of survival. Furthermore, updates are provided on the increasing prevalence of CML and its implications and on the changing cost of care for CML, taking into account the forthcoming impact of availability of generic imatinib. .
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