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Titlebook: Chronic Lymphocytic Leukemia; Michael Hallek,Barbara Eichhorst,Daniel Catovsky Book 2019 Springer Nature Switzerland AG 2019 Chronic Lymph

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https://doi.org/10.1007/978-1-4613-0685-6 remarkable biological and clinical heterogeneity. Key mechanisms underlying CLL onset and progression have been recently dissected. Recent progresses led to the identification of a preneoplastic condition of the disease (i.e., monoclonal B-cell lymphocytosis, MBL) that shed light on very early even
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https://doi.org/10.1007/978-3-658-40787-2edominantly a disease of the elderly with a preponderance of male patients. New evidence suggests that there are variations in gender incidence according to the clinical status of patients, with a higher male:female ratio in the groups with worse prognosis..Full blood counts and a physical examinati
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https://doi.org/10.1007/978-3-658-40787-2road acceptance by physicians and investigators caring for patients with CLL. It is not the aim of the iwCLL guidelines to provide treatment recommendations, but definitions for the initial assessment, indication for treatment, and response assessment of CLL. Recent advances including the discovery
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Reflexion (der Gesellschaft) in Twitter, chromosome 17p (del17p) have a worse response to therapy and significantly shorter progression-free survival (PFS) and overall survival (OS). These genetic abnormalities occur in about 10% of untreated and up to 40% of previously treated patients and they define the “ultra-high risk” group among al
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https://doi.org/10.1007/978-3-663-02889-5 with first-line treatment, the treatment choice of relapsed CLL patients is dependent on several factors, including age, performance status, comorbidities, and duration of response to previous therapy. The outcome of second, and subsequent, lines of therapy is markedly improved by the addition of C
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Reflexion der Forschungsarbeit,are recognized, namely the diffuse large B-cell lymphoma (DLBCL) variant and the rare Hodgkin lymphoma (HL) variant. Histologic documentation is mandatory to diagnose RS. In the presence of clinical features suspicious of RS, diagnosis of transformation and choice of the site of biopsy may take adva
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