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Titlebook: Chronic Lymphocytic Leukemia; Michael Hallek,Barbara Eichhorst,Daniel Catovsky Book 2019 Springer Nature Switzerland AG 2019 Chronic Lymph

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Chronic Lymphocytic Leukemia: Who, How, and Where?t when selecting time and type of treatment in CLL patients. We gained further knowledge on the role of B-cell receptor (BcR) signaling and accumulated several hints supporting its key role in CLL development and progression. This led, for the first time in CLL history, to a targeted treatment appro
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Prognostic Markersr prognosis even with the novel targeted agents and might be considered for experimental approaches or bone marrow transplantation. The possible consequence of the screening results on follow-up, therapy, and quality of life should be discussed with patient and relatives before requesting prognostic
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Initial Therapy of Chronic Lymphocytic Leukemiaed IGHV status the disadvantages of chemoimmunotherapy, such as secondary malignancies or the development of chemo-resistant clones, have to be weighed against its possible benefits, such as the short period of treatment with chemoimmunotherapy compared with the continuous therapy required with nove
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Prolymphocytic Leukaemia of delivering cure. In the last few years many of the molecular mechanisms underlying disease pathogenesis and progression have been revealed and are likely to lead to the development of novel targeted approaches.
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