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Titlebook: Chronic Lymphocytic Leukemia; Michael Hallek,Barbara Eichhorst,Daniel Catovsky Book 2019 Springer Nature Switzerland AG 2019 Chronic Lymph

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发表于 2025-3-21 19:02:06 | 显示全部楼层 |阅读模式
书目名称Chronic Lymphocytic Leukemia
编辑Michael Hallek,Barbara Eichhorst,Daniel Catovsky
视频videohttp://file.papertrans.cn/227/226394/226394.mp4
概述Summarizes current knowledge on all aspects of CLL.Describes the role of different diagnostic procedures.Examines the changing treatment paradigm in CLL and the emergence of new therapeutic targets.Eq
丛书名称Hematologic Malignancies
图书封面Titlebook: Chronic Lymphocytic Leukemia;  Michael Hallek,Barbara Eichhorst,Daniel Catovsky Book 2019 Springer Nature Switzerland AG 2019 Chronic Lymph
描述.This book summarizes current knowledge on chronic lymphocytic leukemia (CLL), taking into account the most recent research. All aspects are considered, including pathophysiology, clinical presentation, diagnosis, prognosis, treatment, follow-up, and complications and their management. Readers will find important information on the various prognostic markers as well as practical guidance on the use of different diagnostic procedures. A key focus of the book is the changing treatment paradigm in CLL as progress in understanding of pathogenesis and pathophysiology leads to the identification of new potential therapeutic targets. General treatment concepts are clearly described, and it is explained how choice of treatment for CLL depends on stage, age, and performance status as well as specific genetic aberrations. In addition, frontline therapeutic strategies for disease relapse, including allogeneic stem cell transplantation, are reported. Looking beyond CLL, the diagnosis and therapyof T-cell prolymphocytic leukemia and T-cell large granular lymphocyte leukemia, two rare CLL-related entities, are addressed... .
出版日期Book 2019
关键词Chronic Lymphocytic Leukemia; Pathophysiology; Prognosis; Treatment; T-cell prolymphocytic leukemia; T-ce
版次1
doihttps://doi.org/10.1007/978-3-030-11392-6
isbn_ebook978-3-030-11392-6Series ISSN 2197-9766 Series E-ISSN 2197-9774
issn_series 2197-9766
copyrightSpringer Nature Switzerland AG 2019
The information of publication is updating

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发表于 2025-3-21 22:08:27 | 显示全部楼层
发表于 2025-3-22 03:14:17 | 显示全部楼层
The Clinical Presentation of CLLedominantly a disease of the elderly with a preponderance of male patients. New evidence suggests that there are variations in gender incidence according to the clinical status of patients, with a higher male:female ratio in the groups with worse prognosis..Full blood counts and a physical examinati
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Guidelines for Diagnosis, Indications for Treatment, Response Assessment, and Supportive Management road acceptance by physicians and investigators caring for patients with CLL. It is not the aim of the iwCLL guidelines to provide treatment recommendations, but definitions for the initial assessment, indication for treatment, and response assessment of CLL. Recent advances including the discovery
发表于 2025-3-22 16:50:43 | 显示全部楼层
Initial Therapy of Chronic Lymphocytic Leukemiaients without very high-risk genomic alterations first-line treatment with chemoimmunotherapy is a well-examined and established standard of care. FCR is the preferred treatment in physically fit patients with mild or no comorbidities. Depending on the burden of comorbidities, less intense chemoimmu
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Autoimmune Cytopenia in Chronic Lymphocytic Leukemiauses, patients with CLL presenting cytopenia require a careful evaluation and an individualized management. The association of CLL with cytopenias of immune origin is based on experts’ consensus, and its impact on patients’ outcome remains controversial. It is widely accepted that treatment should b
发表于 2025-3-23 08:19:11 | 显示全部楼层
Richter Syndromeare recognized, namely the diffuse large B-cell lymphoma (DLBCL) variant and the rare Hodgkin lymphoma (HL) variant. Histologic documentation is mandatory to diagnose RS. In the presence of clinical features suspicious of RS, diagnosis of transformation and choice of the site of biopsy may take adva
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