Titlebook: Chromothripsis; Methods and Protocol Franck Pellestor Book 2018 Springer Science+Business Media, LLC, part of Springer Nature 2018 Massive

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https://doi.org/10.1007/978-1-4842-5581-0alities of the chromosome homologues is preserved. Here we describe strategies for working out the organization of highly rearranged genomes by combining SNP array data with various metaphase FISH methods. This approach can also be used to address some of the uncertainties arising from whole genome

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1064-3745 s and Protocols. serves as a vital resource for cell biologists, molecular biologists, cytogeneticists, and geneticists investigating chromothripsis, but also for students and researchers new to the field of chromothripsis and genomic instability..978-1-4939-9283-6978-1-4939-7780-2Series ISSN 1064-3745 Series E-ISSN 1940-6029

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Chromothripsis978-1-4939-7780-2Series ISSN 1064-3745 Series E-ISSN 1940-6029

intricacy

https://doi.org/10.1007/978-1-4842-5581-0 this process frequently contain micronuclei, which can lead to genomic change and chromothripsis. In this chapter we describe how to induce checkpoint adaptation and detect it by time-lapse video and immunofluorescence microscopy and how to isolate cells undergoing checkpoint adaptation from a total cell population.

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condescend

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