Titlebook: Chromothripsis; Methods and Protocol Franck Pellestor Book 2018 Springer Science+Business Media, LLC, part of Springer Nature 2018 Massive

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https://doi.org/10.1007/978-1-4842-5581-0ds are also useful in detecting chromothripsis in biopsy samples. Issues related to sample collection, storage, and transport, especially with tumor biopsies, may limit the options for sequencing studies, and in such cases, SNP-based microarray may be a viable alternative for detecting chromothripsis.

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Metabolism, Crisis, and Elasticity gametogenesis and early embryonic development may contribute to the emergence of chromothripsis. Multiple lines of evidence support the assumption that chromothripsis may arise more frequently than previously thought in both gametogenesis and early human embryogenesis.

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Potential Role of Chromothripsis in the Genesis of Complex Chromosomal Rearrangements in Human Gamet gametogenesis and early embryonic development may contribute to the emergence of chromothripsis. Multiple lines of evidence support the assumption that chromothripsis may arise more frequently than previously thought in both gametogenesis and early human embryogenesis.

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