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Titlebook: Cholinesterases and Anticholinesterase Agents; George B. Koelle (Professor and Chairman) Book 1963 Springer-Verlag Berlin Heidelberg 1963

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The Active Site of Acetylcholinesterase and Related Esterases and its Reactivity towards Substrates his active site reacts with the substrates and inhibitors of the enzyme. In the present review the term “active site” will refer to those regions of the enzyme surface where the substrate is localized and activated during the enzymic action. No attempt is made to include information on the enzyme, i
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Structure-Activity Relationships of the Reversible Anticholinesterase Agentsdify substantially the pharmacological properties of alkaloids, interest in Structure-Activity Relationships (SAR) has been ever increasing. Never before has the chemically oriented biologist had such a formidable list of compounds to consider. In association with any given pharmacological action, t
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Structure-Activity Relationships of the Organophosphorus Anticholinesterase Agents is amazing that so few scientists have met a premature death as a result. It is remarkable, for example, that the French nobleman and organic chemist . did not succumb to tetraethyl pyrophosphate (TEPP) poisoning in 1854. If this had happened, the toxicity of the anticholinesterase (anti-ChE) agent
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Actions at Autonomic Gangliall as the processes that go on in the autonomic ganglia appear to be of the utmost importance. Because of this, the relation of pre- and postganglionic fibers is very critical, and the ganglionic synapse is provided with elaborate mechanisms for the regulation of its activity.
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