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Titlebook: Cholera Toxins; Keya Chaudhuri,S. N. Chatterjee Book 2009 Springer-Verlag Berlin Heidelberg 2009 Colon.biogenesis.biological functions.cho

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https://doi.org/10.1007/978-3-662-38190-8This concluding chapter of the book presents a glimpse of the authors‘ thoughts on the wealth of knowledge acquired on the nature and function of cholera toxins and the current status of the prevention and cure of the disease cholera.
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An Introduction to Cholera,A brief discussion of the nature of the disease cholera, the seven pandemics experienced, and also the large-scale epidemic caused by the . serogroup O139 around 1992 is presented for the benefit of general readers, including students of microbiology.
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Physikalisch-chemische Rechnungen,The basis of its further subclassification or sub-typing into serogroups, serotypes, biotypes, and phage types has been elucidated. The molecular subtyping of . strains in accordance with (i) plasmid profile analysis, (ii) restriction fragment length polymorphism (RFLP) of . and rRNA genes including
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Chemisch-technische Rechnungen,e on the genetics of the biosynthesis of lipid A of ., the available information on the characteristics and proposed functions of the core polysaccha-ride (core-PS) biosynthetic genes is discussed. The genetic organization encoding the O-antigen polysaccharides (O-PS) of . of serogroups O1 and O139,
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Physikalisch-chemische Rechnungen,, (ii) its antigenic properties, (iii) immunological responses to it, and (iv) its phage receptor activities. The biological functions of the capsular polysaccharides (CPS) of . are also discussed briefly as a relevant topic. The roles of LPS and other extracellular polysaccharides in the (i) intest
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Physikalisch-chemische Rechnungen,rs—cholera toxin (CT) and toxin-coregulated pilus (TCP)—are largely interrelated, and the expression of these two factors is primarily responsible for the virulence of the organism and disease onset. The two horizontally acquired genetic elements are the CTX genetic element containing the . gene and
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https://doi.org/10.1007/978-3-662-43109-2R regulon is controlled by a cascade of regulatory proteins, ToxR, ToxT, and TcpP. In general, the ToxR regulon genes fall into four classes: cholera toxin (CT) genes, toxin-coregulated pilus (TCP) biosynthesis genes, accessory colonization factor (ACF) genes, and the ToxR-activated genes of unknown
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