Titlebook: Cholera Toxins; Keya Chaudhuri,S. N. Chatterjee Book 2009 Springer-Verlag Berlin Heidelberg 2009 Colon.biogenesis.biological functions.cho

有灵感

书目名称Cholera Toxins影响因子(影响力)




书目名称Cholera Toxins影响因子(影响力)学科排名




书目名称Cholera Toxins网络公开度




书目名称Cholera Toxins网络公开度学科排名




书目名称Cholera Toxins被引频次




书目名称Cholera Toxins被引频次学科排名




书目名称Cholera Toxins年度引用




书目名称Cholera Toxins年度引用学科排名




书目名称Cholera Toxins读者反馈




书目名称Cholera Toxins读者反馈学科排名

Keratin

Endotoxin of ,: Physical and Chemical Characterization,the vibrios into some 200 or more serogroups. This chapter presents an account of our current knowledge of the physical and chemical characteristics of the three constituents, lipid A, core polysaccharide (core-PS) and O-antigen polysac-charide (O-PS), of the LPS of . of different serogroups, includ

metropolitan

纬度

Endotoxin of ,: Biological Functions,, (ii) its antigenic properties, (iii) immunological responses to it, and (iv) its phage receptor activities. The biological functions of the capsular polysaccharides (CPS) of . are also discussed briefly as a relevant topic. The roles of LPS and other extracellular polysaccharides in the (i) intest

损坏

Cholera Toxin (CT): Structure,ved using various physicochemical techniques and particularly X-ray crystallography. The holotoxin molecule contains six subunits: one A and five B subunits. The A subunit can be separated into two fragments—A1, containing 192 (positions 1–192 in the sequence) amino acids; and A2, containing 48 (pos

gentle

Cholera Toxin (CT): Organization and Function of the Relevant Genetic Elements,rs—cholera toxin (CT) and toxin-coregulated pilus (TCP)—are largely interrelated, and the expression of these two factors is primarily responsible for the virulence of the organism and disease onset. The two horizontally acquired genetic elements are the CTX genetic element containing the . gene and

gentle

Cholera Toxin (CT): Regulation of the Relevant Virulence Genes,R regulon is controlled by a cascade of regulatory proteins, ToxR, ToxT, and TcpP. In general, the ToxR regulon genes fall into four classes: cholera toxin (CT) genes, toxin-coregulated pilus (TCP) biosynthesis genes, accessory colonization factor (ACF) genes, and the ToxR-activated genes of unknown

motivate

Cholera Toxin (CT): Secretion by the Vibrios, In the bacterial cytosol, the subunits A and B are synthesized as unfolded chains with N-terminal signal peptide. These unfolded chains are then translocated across the inner membrane via the Sec-dependent pathway to reach the periplasmic space. Here, the chains are freed of the signal peptides; th

宽大

Cholera Toxin (CT): Entry and Retrograde Trafficking into the Epithelial Cell, cell membranes through its B pentamers. This attachment takes place preferentially in the lipid raft regions of the cell membrane, which aids in its endocyto-sis via a clathrin- or caveolin-dependent pathway. The CT holotoxin then undergoes retrograde trafficking within the epithelial cell via a gl

inveigh

Cholera Toxin (CT): Immune Response of the Host and Vaccine Production, its adjuvant effect has still remained largely unknown. CT or its component (particularly CTB) also plays a significant role in the preparation of different types of cholera vaccines. While summarizing the important observations that are likely to act as guiding factors in the preparation of vaccin