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Titlebook: Chemosensitivity; Volume II: In Vivo M Rosalyn D. Blumenthal Book 2005 Humana Press 2005 DNA.apoptosis.cell.cell death.chemoresistance.geno

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发表于 2025-3-21 16:35:05 | 显示全部楼层 |阅读模式
书目名称Chemosensitivity
副标题Volume II: In Vivo M
编辑Rosalyn D. Blumenthal
视频video
概述Includes supplementary material:
丛书名称Methods in Molecular Medicine
图书封面Titlebook: Chemosensitivity; Volume II: In Vivo M Rosalyn D. Blumenthal Book 2005 Humana Press 2005 DNA.apoptosis.cell.cell death.chemoresistance.geno
描述A state-of-the art collection of readily reproducible laboratory methods for assessing chemosensitivity in vitro and in vivo, and for assessing the parameters that modulate chemosensitivity in individual tumors. Chemosensitivity,Volume 2: In Vivo Models, Imaging, and Molecular Regulators contains cutting-edge protocols for classifying tumors into response categories and for customizing therapy to individuals. These readily reproducible techniques allow measurements of DNA damage, apoptotic cell death, and the molecular and cellular regulators of cytotoxicity, as well as in vivo animal modeling of chemosensitivity. A companion volume, Volume 1: In Vitro Assays contains in vitro and in vivo techniques to identify which new agents or combination of agents are effective for each type of tumor.
出版日期Book 2005
关键词DNA; apoptosis; cell; cell death; chemoresistance; genomics; imaging; magnetic resonance imaging (MRI); tumo
版次1
doihttps://doi.org/10.1385/1592598897
isbn_softcover978-1-61737-660-3
isbn_ebook978-1-59259-889-2Series ISSN 1543-1894 Series E-ISSN 1940-6037
issn_series 1543-1894
copyrightHumana Press 2005
The information of publication is updating

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Immunodetecting Members of the Bcl-2 Family of Proteinsacellular levels of multiple members of the Bcl-2 protein family can be analyzed simultaneously by immunoblotting and how protein-protein interactions can be studied using immunoprecipitation techniques. In addition, the methodology describes how conformational changes can be observed by immunofluor
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Correlation of Telomerase Activity and Telomere Length to Chemosensitivityerapeutic intervention. Although a telomerase-specific inhibitor has not been found yet, the possible effect of anticancer agents on telomerase inhibition or the alteration of telomere length has been proposed. Recent development of TRAP assay not only increased the sensitivity but also allowed fast
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Overview of Tumor Cell Chemoresistance Mechanismsression. The relevant mechanisms that can contribute to cellular resistance include: increased expression of defense factors involved in reducing intracellular drug concentration; alterations in drug-target interaction; and changes in cellular response, in particular increased cell ability to repair
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Flow Cytometric Monitoring of Fluorescent Drug Retention and Effluxnce in the presence or absence of an efflux blocker such as verapamil. The present chapter discusses some of the flow cytometric methods used for the study of cellular drug retention and the artifacts that may arise in such analysis.
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Limit Cycles and Structural Stability,tic damage, screening of chemicals for genotoxic potential, and for specific purposes such as prediction of the radiosensitivity of tumors and interindividual variation in radiosensi tivity. In its current basic form the CBMN assay can provide, using simple morphological crite ria, the following mea
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https://doi.org/10.1007/978-3-540-33308-1acellular levels of multiple members of the Bcl-2 protein family can be analyzed simultaneously by immunoblotting and how protein-protein interactions can be studied using immunoprecipitation techniques. In addition, the methodology describes how conformational changes can be observed by immunofluor
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Björn Rasch,Wilhelm Hofmann,Ewald Naumannerapeutic intervention. Although a telomerase-specific inhibitor has not been found yet, the possible effect of anticancer agents on telomerase inhibition or the alteration of telomere length has been proposed. Recent development of TRAP assay not only increased the sensitivity but also allowed fast
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Varianzanalyse mit Messwiederholung,tion. Basically, three procedures are described: (1) tissue dissociation and further cultivation on the sensor chip or on Transwell inserts; (2) preparation of tissue slices (300 µm thick) and attachment to the sensor chip or to inserts, and (3) cultivation of cells in dialysis tubes, a procedure ne
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