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Titlebook: Chemosensitivity; Volume II: In Vivo M Rosalyn D. Blumenthal Book 2005 Humana Press 2005 DNA.apoptosis.cell.cell death.chemoresistance.geno

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Flow Cytometric Measurement of Functional and Phenotypic P-Glycoproteincute Myeloid Leukaemia and High Risk Myelodysplastic Syndrome (≫10% blasts). These assays are performed in more than one UK Centre, and hence each assay has been subjected to rigorous reproducibility testing (.).
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Book 2005rameters that modulate chemosensitivity in individual tumors. Chemosensitivity,Volume 2: In Vivo Models, Imaging, and Molecular Regulators contains cutting-edge protocols for classifying tumors into response categories and for customizing therapy to individuals. These readily reproducible techniques
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https://doi.org/10.1007/978-3-540-33308-1tect procaspases and caspases and their activity. Immunodetection and fluorescent substrates are widely accepted methods that are utilized for this purpose. These methods are described in detail in this chapter.
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https://doi.org/10.1007/978-3-540-33310-4nvestigating the mode of action of antitumor drugs. This chapter summarizes protocols for quantitating the level of apoptosis, the activities of acidic sphingomyelinase, neutral sphingomyelinase, glycosylceramide synthase, sphingomyelin synthase, and ceramidase, and the amount of ceramide in tumor xenografts in nude mice.
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Springer Series in Chemical Physicses are used as test examples to predict their associated mechanistic categories. This method of correlating drugs and genes provides a strategy for finding novel biologically significant relationships for molec ular pharmacology.
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Rosalyn D. BlumenthalIncludes supplementary material:
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