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Titlebook: Chemosensitivity Testing in Oncology; Uwe Reinhold,Wolfgang Tilgen Conference proceedings 2003 Springer-Verlag Berlin Heidelberg 2003 brea

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Clinical Significance of Cellular Drug Resistance in Childhood Leukemiaal applications are: prognostic factor for risk-group stratification, tailored chemotherapy for subgroups or individual patients with a specific cellular drug resistance profile, determination of cross-resistance patterns, study of drug interactions, study of resistance modulation or circumvention,
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Jeanne C. Watson,Leslie S. Greenbergs field..Basically two sensor principles or types can be considered: (a) the light-addressed potentiometric sensor (LAPS) and (b) the multisensor array (MSA). Whereas LAPS measures one, MSA registers online many parameters (for instance, impedance, pH, O., temperature). The aim of this chapter is to
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Introduction to Personality Studythe drug was removed. Primary breast cancer cells also responded to chloroacetaldehyde with a marked reduction in ΔpO., followed by a reduced rate of acidification. Comparing the metabolism of doxorubicin-sensitive and -resistant mouse sarcoma S180 cells, the rates of acidification and respiration w
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Julie Goddard,Sudeep Mandal,David Erickson were sensitive to all drugs tested, whereas 33 leukemia and lymphoma patients showed different sensitivities to certain drugs. The method also permitted testing of the effect of new drugs on the proliferation of lymphocytes from hematological cancer patients. This test is sensitive, and 100–1,000 c
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https://doi.org/10.1007/978-1-349-04806-9ds. Of the anti-metabolites tested, 5-FU is relatively disappointing (although still active), and gemcitabine shows considerable activity consistent with a cytotoxic effect. The shape of the inhibition curves is interesting. There is a plateau effect with the topoisomerase inhibitors and vinblastine
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