书目名称 | Chemogenomics |
副标题 | Methods and Protocol |
编辑 | Daniel Merk,Apirat Chaikuad |
视频video | |
概述 | Includes cutting-edge methods and protocols.Provides step-by-step detail essential for reproducible results.Contains key notes and implementation advice from the experts |
丛书名称 | Methods in Molecular Biology |
图书封面 |  |
描述 | This volume presents both theoretical guidance and protocols on chemogenomics including chemogenomics library assembly, compound profiling, and phenotypic assays. The chapters in this book cover topics such as the assembly and use of Kinase Chemogenomics; data mining for chemogenomic compound candidates; protocols for protein family-focused assay systems to profile chemogenomic compounds; functional and target engagement assays in cellular settings for broad characterization; and a discussion on phenotypic assays where chemogenomic sets may be applied. Written in the highly successful .Methods in Molecular Biology. series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls..Cutting-edge and thorough, .Chemogenomics: Methods and Protocols. is a valuable resource for all researchers whoare interested in learning more about this diverse and developing field. . |
出版日期 | Book 2023 |
关键词 | Druggable human proteome; Target validation; Annotated chemogenomic compounds; Targeted chemical librar |
版次 | 1 |
doi | https://doi.org/10.1007/978-1-0716-3397-7 |
isbn_softcover | 978-1-0716-3399-1 |
isbn_ebook | 978-1-0716-3397-7Series ISSN 1064-3745 Series E-ISSN 1940-6029 |
issn_series | 1064-3745 |
copyright | The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Science+Busines |