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Titlebook: Chemical Biology; Methods and Protocol Jonathan E. Hempel,Charles H. Williams,Charles C. Book 2015 Springer Science+Business Media New Yor

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发表于 2025-3-21 16:51:01 | 显示全部楼层 |阅读模式
书目名称Chemical Biology
副标题Methods and Protocol
编辑Jonathan E. Hempel,Charles H. Williams,Charles C.
视频videohttp://file.papertrans.cn/225/224284/224284.mp4
概述Includes cutting-edge methods and protocols.Provides step-by-step detail essential for reproducible results.Contains key notes and implementation advice from the experts.Includes supplementary materia
丛书名称Methods in Molecular Biology
图书封面Titlebook: Chemical Biology; Methods and Protocol Jonathan E. Hempel,Charles H. Williams,Charles C. Book 2015 Springer Science+Business Media New Yor
描述.This volume seeks to enable the discovery of tools in chemical biology by providing readers with various techniques ranging from initial chemical genetic screening to target identification. To successfully highlight the essential components of the chemical biology tool discovery process, the book is organizes into four parts that focus on platforms for molecular discovery in .in vitro .cellular systems, .in vivo. chemical genetic screening protocols, and methods used to discover functional protein targets. Written in the highly successful .Methods of Molecular Biology. series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step readily reproducible laboratory protocols, and key tips on troubleshooting and avoiding known pitfalls..Practical and informative, .Chemical Biology: Methods and Protocols. seeks to improve the success rate of the chemical biology field through the dissemination of detailed and experiential knowledge..
出版日期Book 2015
关键词biological function; chemical; functional protein targets; in vitro cellular systems; in vitro-based com
版次1
doihttps://doi.org/10.1007/978-1-4939-2269-7
isbn_softcover978-1-4939-5284-7
isbn_ebook978-1-4939-2269-7Series ISSN 1064-3745 Series E-ISSN 1940-6029
issn_series 1064-3745
copyrightSpringer Science+Business Media New York 2015
The information of publication is updating

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1064-3745 , .Chemical Biology: Methods and Protocols. seeks to improve the success rate of the chemical biology field through the dissemination of detailed and experiential knowledge..978-1-4939-5284-7978-1-4939-2269-7Series ISSN 1064-3745 Series E-ISSN 1940-6029
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Applying the Logic of Genetic Interaction to Discover Small Molecules That Functionally Interact withat differ the most across the two classes). A technique called compound set enrichment analysis (CSEA), modeled after a widely used method to identify pathways from gene expression data, identifies sets of functionally or structurally related compounds that are statistically enriched among the most
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Dependency Properties and Routed Events, is hampered by resistance. New drug development, like routine screening for drug resistance, has however been hampered by the lack of reliable screening protocols with sufficient throughput. Here we report on two separate in vitro protocols that use fluorescent dyes and allow for standardized drug sensitivity testing on the required scale.
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https://doi.org/10.1007/978-1-4302-1603-2ssay-guided isolation is a rapid and validated method for isolation of compounds with bioactivities. This chapter describes bioassay-guided separation and purification of compounds from the crude extracts of TCMs. Two approaches including size-exclusion chromatography (SEC) and high performance liquid chromatography (HPLC) are described in detail.
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Methods in Molecular Biologyhttp://image.papertrans.cn/c/image/224284.jpg
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