Titlebook: Characterization of Protein Therapeutics using Mass Spectrometry; Guodong Chen Book 2013 Springer Science+Business Media New York 2013 Bio

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书目名称Characterization of Protein Therapeutics using Mass Spectrometry影响因子(影响力)学科排名




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书目名称Characterization of Protein Therapeutics using Mass Spectrometry被引频次




书目名称Characterization of Protein Therapeutics using Mass Spectrometry被引频次学科排名




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书目名称Characterization of Protein Therapeutics using Mass Spectrometry读者反馈学科排名

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The Development and Implementation of LC/MS-Based Bioanalytical Methods for the Quantification of Prate more efficient strategies to identify drug molecules in a cost-effective manner. Although proven treatments such as optimized small molecule drugs continue to provide an effective means for the management of certain medical conditions, alternatives such as engineered protein constructs have als

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Applications of Ion Mobility Mass Spectrometry for Characterization of Protein Therapeutics, Compared with small-molecule pharmaceuticals, recombinant therapeutic proteins are generally complex, heterogeneous, and subject to a variety of enzymatic or chemical modifications during expression, purification, and long-term storage. Because of unique structural features and production processes

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Guodong ChenFirst book to focus on characterization by mass spectrometry of protein drugs.Well-known Volume Editor with strong ties to pharmaceutical industry and analytical chemistry.Internationally recognized c

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仲裁者

Hydrogen/Deuterium Exchange Mass Spectrometry for Protein Higher-Order Structure Characterization,in virtually all cell functions, such as cell division, cell death, immune response, signal transduction, and ligand binding. In contrast to small molecules, proteins are significantly more complicated in structure. In biophysical conditions, proteins fold into unique three-dimensional structures in solution that are flexible and dynamic.

Microgram

Grundbegriffe der Regeltechnik,Historically, new drug entities arose from combinatorial chemistry of small molecules. Today, a rapidly increasing number of new drugs, called biopharmaceuticals, are being developed which are based on biological molecules such as peptides, proteins, and oligonucleotides.