Titlebook: Characterization of Protein Therapeutics using Mass Spectrometry; Guodong Chen Book 2013 Springer Science+Business Media New York 2013 Bio

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Book 2013ers in pharmaceutical research and specialists in analytical sciences will benefit from this book that details step-by-step approaches and new strategies to solve challenging problems related to protein therapeutics research and development.

Aspiration

Grundbegriffe der Regeltechnik,he transfer of ionized non-covalent species with masses well over one million (e.g., 1.5 MDa 24-Mer flavoprotein vanillyl-alcohol oxidase (VAO) from Penicillium simplicissimum [4]) into the gas phase. These advances moved MS into the range of intact protein oligomers and functional machineries.

Anal-Canal

https://doi.org/10.1007/978-3-540-68359-9 strategies and high-quality quantitative bioanalytical methods must be developed and applied throughout the drug discovery and development process in order to inform critical decisions during the selection and characterization of drug candidates.

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Molecular Variants Characterization in Protein Therapeutics Development,wever, the complex nature of biomolecules and the sophisticated manufacturing processes pose more challenges than those for small molecule drugs with regard to analytics for the control of quality, and ultimately efficacy and safety.

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Book 2013ntly utilized analytical techniques in pharmaceutical research and development, mass spectrometry has been widely used in the characterization of protein therapeutics due to its analytical sensitivity, selectivity, and specificity. This book begins with an overview of mass spectrometry techniques as

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dustry and analytical chemistry.Internationally recognized cThis book highlights current approaches and future trends in the use of mass spectrometry to characterize protein therapies. As one of the most frequently utilized analytical techniques in pharmaceutical research and development, mass spect