Titlebook: Challenges and Opportunities for Respiratory Syncytial Virus Vaccines; Larry J. Anderson,Barney S. Graham Book 2013 The Editor(s) (if appl

树上结蜜糖

Consequences of Immature and Senescent Immune Responses for Infection with Respiratory Syncytial Viriated morbidity and mortality. While other factors play a role in the risk these groups assume, shortcomings of the immune response make a substantial contribution to the predisposition to severe disease. Ineffectual antibody production with misdirected cytokine responses and excess inflammation in

流浪者

Respiratory Syncytial Virus Disease: Prevention and Treatmenter the past decade, the most significant advance in the prevention of RSV disease has been the development of high-titered antibody products. Infection control is the only other strategy to prevent RSV disease. A humanized monoclonal antibody directed against the fusion (F) protein palivizumab, (Syn

地壳

Live-Attenuated Respiratory Syncytial Virus Vaccinesuse vaccine-associated enhanced RSV disease; (2) they broadly stimulate innate, humoral, and cellular immunity, both systemically and locally in the respiratory tract; (3) they are delivered intranasally; and (4) they replicate in the upper respiratory tract of young infants despite the presence of

Prognosis

可商量

冰河期

Challenges and Opportunities for Respiratory Syncytial Virus Vaccines978-3-642-38919-1Series ISSN 0070-217X Series E-ISSN 2196-9965

nerve-sparing

HUMID

灾难

Internationale Gerontologische Gesprächeily in terms of the number of genes and proteins. It is also relatively divergent and distinct from the prototype members of the family. In the past 30 years, we have seen a tremendous increase in our understanding of the molecular biology of RSV based on a succession of advances involving molecular

BOLUS

https://doi.org/10.1007/978-3-642-85417-0tract illness in infants <1 year of age. RSV also causes repeat infections and significant disease throughout life. In addition to the young child, persons with compromised immune, pulmonary or cardiac systems, and the elderly have significant risk from infection. Though RSV causes the full spectrum