Titlebook: Challenges and Opportunities for Respiratory Syncytial Virus Vaccines; Larry J. Anderson,Barney S. Graham Book 2013 The Editor(s) (if appl

Spartan

Host Gene Expression and Respiratory Syncytial Virus Infectionene discovery and transcriptome profiling for respiratory syncytial virus (RSV) are discussed in the context of biological relevance for disease intervention in the clinical setting and vaccine development.

细节

Book 2013imal and tissue culture models of RSV infection. It is designed to organize the critical information relevant to RSV vaccine development, facilitate the assimilation of data, and speed progress toward producing a safe and effective vaccine. .

ALIEN

Infinitesimal

Structure and Function of Respiratory Syncytial Virus Surface Glycoproteinsng antibodies induced by infection. In this chapter, we review the structure and function of the RSV surface glycoproteins, including recent X-ray crystallographic data of the F glycoprotein in its pre- and postfusion conformations, and discuss how this information informs antigen selection and vaccine development.

饥荒

离开真充足

C. Brähler,V. Weiss,W. Meyhöferr functions. While the mechanism of action of NS1 and NS2 is a subject of active research, their effect on adaptive immunity is also being recognized. In this review, we discuss various aspects of NS1 and NS2 function with implications for vaccine design.

Asymptomatic

synovium

调整校对

Respiratory Syncytial Virus Mechanisms to Interfere with Type 1 Interferonsr functions. While the mechanism of action of NS1 and NS2 is a subject of active research, their effect on adaptive immunity is also being recognized. In this review, we discuss various aspects of NS1 and NS2 function with implications for vaccine design.

excrete

Consequences of Immature and Senescent Immune Responses for Infection with Respiratory Syncytial Vire better understood. Preventative approaches to decreasing the burden of disease are preferable to therapeutic intervention and effective vaccination strategies will need to target the strengths of the immune responses in these populations.