Titlebook: Central Cholinergic Synaptic Transmission; Michael Frotscher,Ulrich Misgeld Book 1989 Birkhäuser Verlag 1989 Nervous System.Parkinson.anat

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Topography of βNGF receptor-positive and AChe-reactive neurons in the central nervous systemon of βNGF in the central nervous system we have mapped the distribution of βNGF receptors and compared it with that of acetylcholinesterase (AChE), a sensitive enzyme marker for cholinergic neurons.. autoradiography revealed strong and saturable βNGF bnding to several groups of neurons in basal for

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Chol-1: A cholinergic-specific Gganglioside of possible significance in central nervous system neurodentify a group of antigenically-related minor gangliosides (collectively designated Chol-1) that appear to be exclusively localized on cholinergic neurons. The cholinergic-specificity of these antigens has been shown by the following findings. The discovery of a cell surface cholinergic-specific an

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Pharmacological characterization of muscarinic responses in rat hippocampal pyramidal cellsobtained with the M1 antagonist pirenzepine and the M2 antagonist gallamine suggest that an M1 muscarinic receptor is involved in the muscarinic-induced membrane depolarization and blockade of the afterhyperpolarization (AHP). On the other hand, an M2 receptor may be involved in the cholinergic depr

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Mediation of acetylcholine’s excitatory actions in central neuronsch effect on CA1/CA3 population spikes or on the excitatory action of ACh. This is further evidence against the idea that cyclic nucleotides play a major role as cholinergic second messengers. On the other hand, the results of tests with a PKC antagonist sphinganine are in keeping with some involvem

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Cholinergic activation of medial pontine reticular formation neurons ,e phenomena of REM, thus providing the only adequate pharmacological model of this behavioral state. The necessary anatomical substrate, a cholinergic projection to the mPRF was recently demonstrated, however the direct effect of cholinergic agonists on mPRF neurons is unknown. We have examined the