Titlebook: Cellular and Molecular Aspects of Ageing; Valquiria Bueno Book 2024 The Editor(s) (if applicable) and The Author(s), under exclusive licen

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Orientability and Orientations,ent of premature ageing, various cancer predispositions and hereditary diseases. In this chapter, the main causes and consequences of genomic instability are reviewed as well as its association with ageing and age-related conditions.

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https://doi.org/10.1007/978-3-540-77751-9m the beginning or during life of the cell underwent modifications leading e.g. to their aggregation. Eventually, these processes, included in cellular protein homeostasis (proteostasis or proteodynamics) fail to provide enough of new, functional protein molecules characterizing young cell and the cell becomes senescent or dies.

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https://doi.org/10.1007/978-3-540-77751-9t Ther. 7:391, 2022; Partridge in Philosophical transactions of the Royal Society of London Series B, Biological sciences. 365:147–154, 2010;). The biological process of aging is a complex phenomenon that occurs due to the accumulation of a variety of molecular and cellular damages over time.

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Valquiria BuenoFocuses on health ageing.Provides a comprehensive discussion of the hallmarks of ageing.Discusses life style, possible therapies, and clinical trials

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978-3-031-55024-9The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Nature Switzerl

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Spectra and (Co)homology Theories,ath. The further understanding of cellular and molecular aspects of ageing could predict the onset of diseases in advance, prevent functional decline and identify targets for interventions focused in healthy ageing. The hypothesis that organismal ageing and dysfunction is influenced by the accumulat

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