| 书目名称 | Cells and Culture | | 副标题 | Proceedings of the 2 | | 编辑 | Thomas Noll | | 视频video | | | 概述 | A Comprehensive review of the latest research and developments in the field of animal cell technology..A unique collection of papers on animal cell technology for industrialists..Practical information | | 丛书名称 | ESACT Proceedings | | 图书封面 |  | | 描述 | Regeneration of tissue to replace damaged or injured tissue is the goal of t- sue engineering. Biomaterials like polyglycolic acid, collagen and small-intestinal submuscosa provide a temporary scaffold to guide new tissue growth and or- nization. Typically, they need to be biodegradable, showing good cell atta- ment and proliferation and they should possess appropriate mechanical properties (Kim et al. , 2000). Synthetic polymers ful ll most of these requirements but lack cell-adhesion peptides on their surface to enhance cell attachment. Ce- adhesion peptides are present in ECM proteins like collagen and elastin. Thus a synthetic polymer coated with ECM proteins would result in a scaffold that mimics the natural cellular environment with enhanced cell attachment and p- liferation. The new bioactive scaffold will be made by combining a synthetic polymer coated with a layer of recombinant ECM proteins produced by CHO cells. The rst step consists of identifying polymers that give best results in terms of CHO cell attachment and growth. Classical techniques to determine biomass are inappropriate to evaluate 3-D structures. Thus a screening system based on stable GFP expressing CHO cel | | 出版日期 | Conference proceedings 2010 | | 关键词 | Proteomics; bioinformatics; biotechnology; cell; cell culture; glycoprotein; microarray; physiology; protein | | 版次 | 1 | | doi | https://doi.org/10.1007/978-90-481-3419-9 | | isbn_softcover | 978-94-024-0520-0 | | isbn_ebook | 978-90-481-3419-9 | | copyright | Springer Science+Business Media B.V. 2010 |
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发表于 2025-3-21 16:06:31
