书目名称 | Cell Signaling During Mammalian Early Embryo Development |
编辑 | Henry J. Leese,Daniel R. Brison |
视频video | |
概述 | Edited by two leaders in the field of reproductive biology.One of the first books on cell signaling in early embryo development.Covers signaling events from the zygote embryo through to the blastocyst |
丛书名称 | Advances in Experimental Medicine and Biology |
图书封面 |  |
描述 | The book considers signaling events from the zygote embryo through to the blastocyst with relevant data from embryonic stem (ES) cells, including dialogue with the extracellular environment and with the maternal tract during the implantation process. Application of the knowledge described to improve the success of human and animal assisted conception is considered where appropriate, but the focus is largely on fundamental rather than applied cell/molecular biology, as this is the area that has historically been neglected. While the general features of metabolism during preimplantation development are well established, especially in terms of nutrient requirements, uptake and fate, remarkably little is known about early embryo signaling events, intracellular or intercellular, between individual embryos in vitro or with the female reproductive tract in vivo. This contrasts with the wealth of information on cell signaling in somatic cells and tissues, as a glance at any textbook of biochemistry illustrates. This lack of information is such that our understanding of the molecular cell biology of early embryos -- a prerequisite to defining the mechanisms which regulate development at thi |
出版日期 | Book 2015 |
关键词 | assisted reproductive technology; blastocyst; cell signaling; embryo-maternal dialogue; preimplantation |
版次 | 1 |
doi | https://doi.org/10.1007/978-1-4939-2480-6 |
isbn_softcover | 978-1-4939-4828-4 |
isbn_ebook | 978-1-4939-2480-6Series ISSN 0065-2598 Series E-ISSN 2214-8019 |
issn_series | 0065-2598 |
copyright | The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Science+Busines |