Titlebook: Cell Death; Mechanism and Diseas Hao Wu Book 2014 Springer Science+Business Media New York 2014 Apoptosis.Cell death.Receptors

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Historical Perspective: The Seven Ages of Cell Death Research,he same terms for publications 25 years ago yields only 42 publications. Although it has been recognised for over 150 years that death of some of an organism’s cells is a normal physiological process, widespread interest in the field has only come about in recent times, once the mechanisms that impl

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The Intrinsic Apoptotic Pathway, and is involved in the pathogenesis of human diseases ranging from immune disorders and neurodegeneration to cancer. Over the last two decades, much has been learned about the molecular basis of this pathway as well as its delicate regulatory mechanisms. The central role of the cellular organelle,

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Bcl-2 Family and Their Therapeutic Potential,s develop when cells bypass regulated cell death and grow faster than they die, while in degenerative diseases there is too much cell death. Thus understanding how Bcl-2 proteins modulate cell survival will provide novel important insight into therapeutic targets, as evidenced by recent successes sp

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IAP Proteins and Their Therapeutic Potential,ed cell death can lead to developmental defects, neuropathies, infections, and cancer. Inhibitor of apoptosis (IAP) proteins are evolutionarily conserved regulators of cell death with impact on numerous cellular processes. Initially identified as inhibitors of cell death during viral infection, IAP