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Titlebook: Cell Death; Mechanism and Diseas Hao Wu Book 2014 Springer Science+Business Media New York 2014 Apoptosis.Cell death.Receptors

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Neuronal Death Mechanisms in Development and Disease, such as modulating synaptic plasticity or mediating neurite pruning to ensure the establishment of precise neuronal circuitry. Lastly, we provide a broad overview of the complex and multiple cell death mechanisms seen in neurons after injury and in neurodegenerative diseases.
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Book 2014rgeted therapies aimed at interdicting cell death machineries are also discussed extensively. The molecular mechanisms that underlie apoptotic cell death are illustrated from the perspectives of both the intrinsic, mitochondrial apoptotic pathway and the extrinsic, death receptor pathway. Key player
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Maria Renata da Cruz Duran,Adnan Qayyum DNA damage and the molecular mechanisms that mediate p53-dependent and -independent apoptosis. Moreover, we discuss the signals that trigger the DDR during malignant propagation and the importance of DNA damage-mediated apoptosis in preventing tumorigenesis.
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Historical Perspective: The Seven Ages of Cell Death Research,ement it were elucidated and abnormalities in the physiological cell death process were linked to human disease. The stages of research into the field of cell death can be likened to the ages of man, except in this case there was an extraordinarily long infancy, and despite the current maturity of the field, it continues to rapidly grow.
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