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Titlebook: Cell Activation and Apoptosis in HIV Infection; Implications for Pat Jean-Marie Andrieu,Wei Lu Book 1995 The Editor(s) (if applicable) and

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One Legacy of Paul F. Brandweins, recent reports indicate that these defects may be due to the inappropriate triggering of activation-induced cell death or apoptosis in T cells from such individuals whenstimulated with specific antigen or certain mitogens (.., 1992; .., 1992; .; Oyaizu ., 1993). Thus, the progressive depletion of
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https://doi.org/10.1007/978-90-481-3815-9 induce in about ten years a progressive and complete loss of immune competence in the infected host by causing the loss of the lymphocyte population that plays a central role in the control of the immune response, the CD4. T helper cells..
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https://doi.org/10.1007/978-90-481-3815-9 immune system and infectious agent: This noncytopathic virus infects macrophages, antigen presenting cells, helper T cells and other host cells which are then destroyed by the CD8. T cell immune response. Thus, HIV infects some of the key cells involved in immune reactions and therefore induces the
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Transoceanic Voyaging in the Pacificelf-tolerance by T cells. The basic genetic defect underlying autoimmune disease has been identified as a mutation of the Fas apoptosis antigen in MRL-. mice or a mutation of the Fas ligand in C3H-. mice. In MRL-. mice, the . mutation results from a 5.3 kb insertion of the . retrotransposon in the s
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The Marine Geoid and Satellite Altimetry,nodeficiency virus (HIV) infection. The concept that immunopathologic processes cause immune suppression provides a further rationale for the use of agents such as cyclosporin A (CsA) or tacrolimus (formerly known as FK506) early in HIV infection to reduce cytotoxic CD8. T cell-mediated destruction
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https://doi.org/10.1007/978-90-481-8766-9ins known as the cyclophilins is necessary for viral infectivity and perhaps of importance to the immunopathology associated with HIV infection. Cyclophilins are ubiquitous prolyl isomerases thought to function as chaperones. Members of this family of proteins are required for the immunosuppression
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https://doi.org/10.1007/978-1-4615-1995-9AIDS; HIV; HIV infection; Pathogene; development; infection
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