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Titlebook: Cardiovascular Effects of Dihydropyridine-Type Calcium Antagonists and Agonists; Albrecht Fleckenstein,Cornelius Breemen,Friedrich Confer

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Chemistry of Dihydropyridines [1–4] part of his “Habilitation” work at the University of Leipzig, where he was a young assistant lecturer in the Chemistry Institute. The results of this work were first published by Hantzsch in the year 1882 [5].
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The Dihydropyridine Receptorsthe chapter will complement the contributions of Glossmann, Nayler and Schwartz (this volume) and the previously published reviews of 1,4-dihydropyridine (DHP) binding studies (Meyer et al. 1983; Janis and Triggle 1984; Triggle and Janis 1984).
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The Effects of 1,4-Dihydropyridine Type Ca2+-Channel Antagonists and Agonists on Intracellular [Ca2+nd Bay k 8644. Our primary tool in this work has been the Ca.-sensitive photoprotein, aequorin (see Blinks et al. 1982), which we have used to observe the changes in cytoplasmic free [Ca.) that accompany the twitch contraction of mammalian ventricular muscle.
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Myocardial Effects of Dihydropyridines in Patientsschemia is present. This the more so since Lichtlen (1984) and Buhler (1984), respectively, will talk about the effects of these compounds on the coronary vasculature and on the peripheral vasculature in hypertension.
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