Titlebook: Cardiovascular Effects of Dihydropyridine-Type Calcium Antagonists and Agonists; Albrecht Fleckenstein,Cornelius Breemen,Friedrich Confer

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Deterrence Stability in South Asia Today,nd Bay k 8644. Our primary tool in this work has been the Ca.-sensitive photoprotein, aequorin (see Blinks et al. 1982), which we have used to observe the changes in cytoplasmic free [Ca.) that accompany the twitch contraction of mammalian ventricular muscle.

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A Final Solution for a Big Challengests some new results are coming along with this exciting type of new drugs. Discussing Ca agonistic drugs opens the window for new indications — even those not covered by present drugs. Let us hope that we go for a developement of Ca agonistic drugs in a few years as intensively as we did and still

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Participation under Tricky Conditions contractile tension development. The elucidation of the intermediate and the final links of this chain, i.e. of the interaction of Ca. ions with intracellular organelles and with the protein constituents of the contractile system, has progressed tremendously during the past 3 decades. The name of S

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Achim Brunnengräber,Miranda Schreurslong-lasting openings and very brief closings that appear only rarely (mode 2), and records that lack openings because of channel unavailability (mode 0). The dihydropyridine Ca agonist Bay K 8644 enhances Ca channel current by promoting mode 2, while the Ca antagonists nitrendipine and nimodipine r

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A Final Solution for a Big Challenge that there are two components to this Ca entry process. The first is the permeation of Ca ions through the proteolipid plasmalemma mediated by a resting Ca leak and several excitable channels. The second component is the diffusion through a narrow space near the inner surface of the membrane which

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https://doi.org/10.1007/978-3-658-08962-7ed in mammalian central neurones. Their properties have been inferred from a variety of Ca-dependent voltage-transients (reviewed by Llinas and Walton 1980); and Ca-currents have been recorded directly in voltage-clamp experiments on spinal motoneurones (Schwindt and Crill 1980a,b), in hippocampal p

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,India’s Changing Views of Arms Control,the chapter will complement the contributions of Glossmann, Nayler and Schwartz (this volume) and the previously published reviews of 1,4-dihydropyridine (DHP) binding studies (Meyer et al. 1983; Janis and Triggle 1984; Triggle and Janis 1984).