Titlebook: Cardiovascular Calcification and Bone Mineralization; Elena Aikawa,Joshua D. Hutcheson Book 2020 Springer Nature Switzerland AG 2020 Aorti

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Heart-Attack

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Differential Mechanisms of Arterial and Valvular Calcificationdeath worldwide. Arterial calcification impairs vascular resistance, thereby contributing to heart failure, and increases atherosclerotic plaque rupture risk contributing to heart attack and stroke. Calcification of the aortic valve leads to narrowing of the valve opening, reduced blood flow, and he

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Calcifying Extracellular Vesicles: Biology, Characterization, and Mineral Formationmplicated in disease progression. EVs are secreted by various cell types and can be assayed from tissue, cell culture media, and biological fluids collected from animals and human subjects. A special subtype of EVs known as matrix vesicles has been studied as nucleating sites for mineralization in s

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Role of Biomechanical Stress and Mechanosensitive miRNAs in Calcific Aortic Valve Diseasee, the current therapeutic options lack medical therapies and are limited to aortic valve (AV) replacement. AV calcification occurs preferentially in the fibrosa side of the valve, which is exposed to unstable hemodynamic conditions. In contrast, the ventricularis side is exposed to more stable hemo

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The Role of Calcification in Peripheral Artery Diseaselity (Shu and Santulli, Atherosclerosis. 275:379–81, 2018; Norgren et al., J Vasc Surg. 45 Suppl S:S5–67, 2007). Arterial calcification has emerged as a key predictor of poor outcomes in patients with PAD. The medial calcification most commonly identified in lower extremity arteries represents a pat

Agronomy

Bioprosthetic Heart Valve Calcification: Clinicopathologic Correlations, Mechanisms, and Preventionalve. Their major limitation is structural degeneration caused by calcification. Calcification following implantation occurs in a tissue made vulnerable to calcification by the chemical treatment and physical changes induced during valve fabrication and their consequences following implantation. Dat

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