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Titlebook: Cardiac Energetics; Basic Mechanisms and R. Jacob,Hj. Just,Ch. Holubarsch Conference proceedings 1987 Springer-Verlag Berlin Heidelberg 198

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楼主: Tyler
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Orthonormal Series and Approximation,The investigations were performed on male rats with renal (Goldblatt II) and spontaneous (Aoki-Okamoto) hypertension at different stages of haemodynamic overload. Two groups of SHR were submitted to intermittent feeding (SHR IF); one group received additionally the .-blocking agent atenolol (50 mg/k
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Nonparametric Regression for Small Samples, state equation of the intertropomyosin-interaction model of Tawada et al. [35] was extended by introducing the rates of cross-bridge cycling of myofibrils composed of V-1 or V-3 and the concentration of the myosin isoenzymes. Cross-bridge cycling rates of 1.0 or 0.7 were derived for myofibrils comp
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978-3-662-11291-5Springer-Verlag Berlin Heidelberg 1987
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The mechanism of muscle contraction. Biochemical, mechanical, and structural approaches to elucidate cross-bridges which extend from the myosin filaments and cyclically interact with the actin filaments as ATP is hydrolysed. Current biochemical studies suggest that the myosin cross-bridge exists in two main conformations. In one conformation, which occurs in the absence of MgATP, the cross-bridge
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Energetics studies of muscles of different typesng muscles. In resting fast-twitch skeletal muscle the chemical potential of ATP obtained from the measured intracellular pH, ATP and inorganic phosphate concentrations and from the ADP concentrations calculated from the position of the creatine kinase equilibrium was −72 kJ/mol ATP. This high value
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High energy phosphate of the myocardium: Concentration versus free energy changea free energy and chemical potential respectively, of ATP of about 60 kJ/mol. This energy level does not need to be correlated with tissue ATP content and can also be reached with markedly lower amount of tissue ATP. With graded hypoxia, this energy level drops to 50 to 40 kJ/mol without a correspon
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Mechanical determinants of myocardial energy turnoverxperimental result corresponds to predictions from a time varying elastance model of the mechanical and energetic properties of the left ventricle. To assess the validity of this model for cardiac muscle in general, experiments were designed to investigate whether mechanical and energetic behaviour
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Cardiac energetics and the Fenn effecth subdivisions are often thermodynamically misleading. There is an activation term that relates to Ca . release and retrieval, a work term and a stress or load-dependent heat term. The work and load-dependent energy terms presumably have their origin in the actin-activated myosin ATPase. It can be s
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