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Titlebook: Carbohydrate-Based Interactions at the Molecular and the Cellular Level; Kieran L. Hudson Book 2018 Springer International Publishing AG,

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书目名称Carbohydrate-Based Interactions at the Molecular and the Cellular Level
编辑Kieran L. Hudson
视频video
概述Nominated as an outstanding Ph.D. thesis by the University of Bristol, UK.Presents an in-depth analysis of carbohydrate binding by proteins.Offers new insights into non-covalent interactions in chemis
丛书名称Springer Theses
图书封面Titlebook: Carbohydrate-Based Interactions at the Molecular and the Cellular Level;  Kieran L. Hudson Book 2018 Springer International Publishing AG,
描述.This book offers a clearly written and highly accessible account of two different aspects of carbohydrate chemistry. Carbohydrates are an essential component of life and have many important biological functions, but the details of how carbohydrates interact with other biomolecules to mediate biological signalling remain unclear. Firstly, this thesis details innovative methods to mine protein structural data to uncover new features of carbohydrate-based interactions. It also explains these findings using physical chemistry, specifically CH–pi interactions associated with the properties of the interacting partners. .Carbohydrates are also critical for tissue growth and development, yet are underexploited in the materials science that underpins much of regenerative medicine. As such, the second part of this thesis describes a diverse array of techniques ranging from synthetic chemistry and enzymatic synthesis to prepare a wide variety of carbohydrates, and materials chemistry to prepare glycosylated hydrogels, to cell biology to determine the effects on cellular development for tissue engineering applications..
出版日期Book 2018
关键词Protein-carbohydrate Interactions; Aromatic Interactions; Ligand Binding; Peptide-based Materials; Smart
版次1
doihttps://doi.org/10.1007/978-3-319-77706-1
isbn_softcover978-3-030-08517-9
isbn_ebook978-3-319-77706-1Series ISSN 2190-5053 Series E-ISSN 2190-5061
issn_series 2190-5053
copyrightSpringer International Publishing AG, part of Springer Nature 2018
The information of publication is updating

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https://doi.org/10.1007/978-88-470-2610-0rystal structures containing carbohydrates. I then correlated the distributions of amino acids around carbohydrates to models of carbohydrate properties to identify trends. Finally, it describes studies to confirm the findings about carbohydrate–aromatic interactions by NMR spectroscopy. This first
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